Why pushing sensitivity of assays

First published: 2021-07-09

Last Edited: 2023-01-14

Number of edits: 4

Normal assays for biomolecules have detection thresholds of around $p M$ . However, a tumor of $1 m m^{3}$ contains around 1 million cells. Each secrete around 5000 proteins, and the human body has around 5 liters of blood. This gives around:

10^{6} \frac{prot}{m l}

, or

2 \cdot 10^{- 15} M

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Why pushing sensitivity of assays

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